Selected publications


Wu W., Pott D., Chiastra C., Petrini L., Pennati G., Dubini G., Steinseifer U., Sonntag S., Kuetting M., Migliavacca F; Fluid–Structure Simulation of a Transcatheter Aortic Valve Implantation: Potential Application to Patient-Specific Cases. In book: Computer Methods in Biomechanics and Biomedical Engineering, 2017; pp. 93-98.

Büsen M., Arenz C., Neidlin M., Liao S., Schmitz-Rode T., Steinseifer U., Sonntag S; Development of an In Vitro PIV Setup for Preliminary Investigation of the Effects of Aortic Compliance on Flow Patterns and Hemodynamics. Cardiovascular Engineering and Technology, 2017; 8(3), 368-377.

Borchardt R., Sonntag S., Ritter P., Boehning F., Groß-Hardt S., Hesselmann F., Steinseifer U., Verbelen T., Meyns B., Kaufmann T.; In-Vivo Study of a Novel Long-Term Lung Support Device for PAH, Bridge-to-Transplant and Bridge-to-Candidacy. The Journal of Heart and Lung Transplantation, 2017; 36(4), S74-S75.

Karasgiannidis C., Straussmann S., Brodie D, Ritter P., Larson A., Borchardt R., Windisch W., Impact of membrane lung surface area and blood flow on extracorporeal CO2 removal during severe respiratory acidosis, Intensive Care Medicine Experimental, 2017.

Wappenschmidt J., Sonntag S., Buesen M., Gross-Hardt S., Kaufmann T., Schmitz-Rode T., Autschbach R., Goetzenich A; Fluid Dynamics in Rotary Piston Blood Pumps, Annals of Biomedical Engineering, 2017.

Assmann A., Struß M., Schiffer F., Heidelberg F,Munocata H., Timchenko E.; Timschenko D., Kaufmann T., Huynh.K, Sugimura Y., Leidl Q., Pinto A, Stoldt V; Improvement of the in vivo cellular repopulation of decellularized cardiovascular tissues by a detergent-free, non-proteolytic, actin-disassembling regimen, journal of Tissue Engineering and Regenerative Medicine, 2017.

Vodiskar J.; Kutting M., Steinseifer U., Vazquez-Jimenez J., Sonntag S.; Using 3D Physical Modeling to Plan Surgical Corrections of Complex Congenital Heart Defects, The Thoracic and Cardiovascular Surgeon, 2017.


Wu W., Mazza B., Sironi T., Dordoni E., Chiastra C., Petrini L., Pennati G., Dubini G., Steinseifer U., Sonntag S; Kuetting M., Migliavacca F. Fluid–Structure Interaction Model of a Percutaneous Aortic Valve: Comparison with an In Vitro Test and Feasibility Study in a Patient-Specific Case, Annals of Biomedical Engineering, 2016.

Neidlin M., Sonntag S., Schmitz-Rode T., Steinseifer U., Kaufmann T.; Investigation of hemodynamics during cardiopulmonary bypass: A multiscale multiphysics fluid–structure-interaction study, Medical Engineering & Physics, 2016.

Liam S., Simpson B., Neidlin M., Kaufmann T., Li Z., Woodruft M., Gregory S; Numerical prediction of thrombus risk in an anatomically dilated left ventricle: the effect of inflow cannula designs, BioMedical Engineering OnLine, 2016.

Neidlin M, Corsini C, Sonntag S, Schulte-Eistrup S, Schmitz-Rode T, Steinseifer U, Pennati G, Kaufmann T; Hemodynamic analysis of outflow grafting positions of a ventricular assist device using closed-loop multiscale CFD simulations: Preliminary results. Journal of Biomechanics, 2016; 49(13).


Schlanstein P., Hesselmann F., Jansen S., Gemsa J., Kaufmann T., Klaas M, Roggenkamp D., Schröder W., Schmitz-Rode T., Steinseifer U., Arens J; Particle Image Velocimetry Used to Qualitatively Validate Computational Fluid Dynamic Simulations in an Oxygenator: A Proof of Concept, Cardiovascular Engineering and Technology, 2015.

Stroessel P., RasoR. KaufmannT., Grass R.; Stark W; Fibers Mechanically Similar to Sheep Wool Obtained by Wet Spinning of Gelatin and Optional Plasticizers, Macromolecular Materials und Engineering, 2015.

Jansen-Park S-H., Mahmood M., Müller J., Turnhoff L., Smitz-Rode T., Steinseifer U., Sonntag S; Effects of Interaction Between Ventricular Assist Device Assistance and Autoregulated Mock Circulation Including Frank–Starling Mechanism and Baroreflex, Artif Organs. 2015.

Gester K., Birtel S., Clauser J., Steinseifer U., Sonntag S; Real-Time Visualization of Platelet Interaction with Micro Structured Surfaces, Artif. Organs. 2015.

Sonntag SJ, Kütting M, Ghalati PF, Kaufmann T, Vázquez-Jiménez J, Steinseifer U, Vodiskar J. Effect of pulmonary conduit oversizing on hemodynamics in children. Int J Artif Organs. 2015.

Neidlin M, Büsen M, Brockmann C, Wiesmann M, Sonntag SJ, Steinseifer U, Kaufmann TA. A numerical framework to investigate hemodynamics during endovascular mechanical recanalization in acute stroke. International Journal for Numerical Methods in Biomedical Engineering. 2015.

Gester K, Lüchtefeld I, Büsen M, Sonntag SJ, Linde T, Steinseifer U, Cattaneo G. In Vitro Evaluation of Intra-Aneurysmal, Flow-Diverter-Induced Thrombus Formation: A Feasibility Study. American Journal of Neuroradiology. 2015.

Wu W, Pott D, Mazza B, Sironi T, Dordoni E, Chiastra C, Petrini L, Pennati G, Dubini G, Steinseifer U, Sonntag SJ, Kuetting M, Migliavacca F. Fluid-Structure Interaction Model of a Percutaneous Aortic Valve: Comparison with an In Vitro Test and Feasibility Study in a Patient-Specific Case. Ann Biomed Eng. 2015.

Büsen M, Kaufman TAS, Neidlin M, Steinseifer U, Sonntag SJ. In vitro 3D flow investigations in the aortic arch during cardiopulmonary bypass with Stereo-PIV. J Biomech. 2015.

Hsu P-L, McIntyre M, Boehning F, Dang W, Parker J, Autschbach R, u. a. In-Series Versus In-Parallel Mechanical Circulatory Support for the Right Heart: A Simulation Study. Artif Organs. 2015.


Sonntag SJ, Kaufmann TAS, Buesen MR, Laumen M, Gräf F, Linde T, Steinseifer U. Numerical washout study of a pulsatile Total Artificial Heart. Int J Artif Organs 2014.

Sonntag SJ, Li W, Kaestner W, Becker M, Büsen MR, Marx N, Merhof D, Steinseifer U. Combined Computational and Experimental Approach to Improve the Assessment of Mitral Regurgitation by Echocardiography. Ann Biomed Eng. 2014.

Kaufmann TAS, Neidlin M, Buesen M, Sonntag SJ, Steinseifer U. Implementation of Intrinsic Lumped Parameter Modeling into Computational Fluid Dynamicy Studies of Cardiopulmonary Bypass. J Biomech. 2014.

Kaufmann TAS, Schlanstein P, Moritz A, Steinseifer U. Development of a hemodynamically optimized outflow cannula for cardiopulmonary bypass. Artif. Organs 2014.

Neidlin M, Steinseifer U, Kaufmann TAS. A multiscale 0-D/3-D approach to patient-specific adaptation of a cerebral autoregulation model for computational fluid dynamics studies of cardiopulmonary bypass. J Biomech. 2014.

Neidlin M, Jansen S, Steinseifer U, Moritz A, Kaufmann TAS. Design Modifications and Computational Fluid Dynamic Analysis of an Outflow Cannula for Cardiopulmonary Bypass. Ann Biomed Eng. 2014

Kaufmann TAS, Leisser C, Gemsa J, Steinseifer U. Analysis of emboli and blood flow in the ophthalmic artery to understand retinal artery occlusion. Biomed Tech (Berl) 2014.

Kaufmann TAS, Steinseifer U, Schmitz-Rode T. Computergestützte Modellierung in der kardiovaskulären Medizintechnik In: Braunschweigische Wissenschaftliche Gesellschaft: Jahrbuch 2013. J. Cramer Verlag; ISBN: 978-3-934656-33-8, 2014

Schlanstein PC, Borchardt R, Mager I, Schmitz-Rode T, Steinseifer U, Arens J. Gas exchange efficiency of an oxygenator with integrated pulsatile displacement blood pump for neonatal patients. Int J Artif Organs 2014.

Boehning F, Mejia T, Schmitz-Rode T, Steinseifer U. Hemolysis in a laminar flow-through couette shearing device: an experimental study. Artif Organs. 2014.

Hsu P-L, Graefe R, Boehning F, Wu C, Parker J, Autschbach R, u. a. Hydraulic and hemodynamic performance of a minimally invasive intra-arterial right ventricular assist device. Int J Artif Organs. 2014.


Boehning F, Timms D, Hsu P-L, Schmitz-Rode T, Steinseifer U. Experimental and analytical performance evaluation of short circular hydrodynamic journal bearings used in rotary blood pumps. Artif Organs. 2013.

Sonntag SJ, Kaufmann TAS, Buesen MR, Laumen M, Linde T, Schmitz-Rode T, Steinseifer U. Simulation of a pulsatile total artificial heart: Development of a partitioned Fluid Structure Interaction model. J Fluid Struct. 2013.

Wagner G, Schlanstein P, Fiehe S, Kaufmann TAS, Kopp R, Bensberg R, Schmitz-Rode T, Steinseifer U, Arens J. A novel approach in extracorporeal circulation: individual, integrated, and interactive heart-lung assist (I3-Assist). Biomed Tech (Berl) 2013.

Hillebrand J, Dzemali O, Konerding MA, Koch M, Kaufmann TAS, Steinseifer U, Moritz A. Anatomical and flow dynamic considerations for safe right axillary artery cannulation. J Thor Cardiovasc Surg. 2013.

Borchardt R; Schlanstein P; Mager I; Arens J; Schmitz-Rode T; Steinseifer U. In-vitro-Testung eines Oxygenators mit integrierter pulsatiler Pumpe für pädiatrische Anwendungen. Kardiotechnik 2013.


Kaufmann TAS, Schmitz-Rode T, Steinseifer U. Implementation of Cerebral Autoregulation into Computational Fluid Dynamics Studies of Cardiopulmonary Bypass. Artif Organs. 2012.

Kaufmann TAS, Wong KC, Schmitz-Rode T, Steinseifer U. Mimicking of Cerebral Autoregulation by Flow-Dependent Cerebrovascular Resistance: a Feasibility Study. Artif Organs. 2012.

Kaufmann TAS, Schmitz-Rode T, Moritz A, Steinseifer U. Mimicking of the Human Regulatory System by Flow-Dependent Vascular Resistance: A Feasibility Study. In: C.T. Lim and J.C.H. Goh (Eds.): WCB 2010 IFMBE Proceedings 31/LXV, 2012.

Borchardt R, Schlanstein P, Mager I, Arens J, Schmitz-Rode T, Steinseifer U. In Vitro Performance Testing of a Pediatric Oxygenator With an Integrated Pulsatile Pump. ASAIO Journal. 2012.


Sonntag SJ. Numerische Simulation des Blutflusses an insuffizienten Mitralklappen, in Heinz Handels; Jan Ehrhardt; Thomas Martin Deserno; Hans-Peter Meinzer & Thomas Tolxdorff, ed., Bildverarbeitung für die Medizin, Springer, 2011.

Kaufmann TAS, Laumen M, Schlanstein P, Schmitz-Rode T, Steinseifer U. Combining imaging, CAD and CFD techniques to improve patient outcome during cardiopulmonary bypass and ventricular assist device support. Computer Aided Medical Engineering. 2011.

Kaufmann TAS, Graefe R, Hormes M, Schmitz-Rode T, Steinseifer U. Computational Fluid Dynamics in Biomedical Engineering. In: Computational Fluid Dynamics: Theory, Analysis and Applications. Murphy AD (Edt.), Nova Publishers; ISBN: 978-1-61209-276-8, 2011.

Kaufmann TAS, Linde T, Cuenca-Navalon E, Schmitz C, Hormes M, Schmitz-Rode T, Steinseifer U. Transient, Three-Dimensional Flow Field Simulation through a Mechanical, Trileaflet Heart Valve Prosthesis. ASAIO Journal. 2011.

Kaufmann TAS, Gester K, von Trotha K-T, Butz N, Neumann UP, Schmitz-Rode T, Steinseifer U. Numerical simulation of suture tension dependent on fiber material and puncture modalities. In: Biomedical Engineering (MECBME), 2011 1st Middle East Conference on, 2011.

Hormes M, Borchardt R, Mager I, Schmitz Rode T, Behr M, Steinseifer U. A validated CFD model to predict O2 and CO2 transfer within hollow fiber membrane oxygenators. Int J Artif Organs. 2011.

Boehning F, Timms DL, Amaral F, Oliveira L, Graefe R, Hsu P-L, u. a. Evaluation of hydraulic radial forces on the impeller by the volute in a centrifugal rotary blood pump. Artif Organs. 2011.


Laumen M, Kaufmann TAS, Timms D, Schlanstein P, Jansen S, Gregory S, Wong K, Schmitz-Rode T, Steinseifer U. Flow analysis of ventricular assist device inflow and outflow cannula positioning using a naturally shaped ventricle and aortic branch. Artificial Organs. 2010.

Graefe R, Borchardt R, Arens J, Schlanstein P, Schmitz-Rode T, Steinseifer U. Improving oxygenator performance using computational simulation and flow field-based parameters. Artif Organs. 2010.

Borchardt R, Schlanstein P, Arens J, Graefe R, Schreiber F, Schmitz-Rode T, et al. Description of a flow optimized oxygenator with integrated pulsatile pump. Artif Organs. 2010.


Kaufmann TAS, Hormes M, Laumen M, Timms DL, Linde T, Schmitz-Rode T, Moritz A, Dzemali O, Steinseifer U. Flow Distribution during Cardiopulmonary Bypass in Dependency on the Outflow Cannula Positioning. Artif Organs. 2009.

Kaufmann TAS, Hormes M, Laumen M, Timms DL, Linde T, Schmitz-Rode T, Moritz A, Dzemali O, Steinseifer U. The impact of Aortic/Subclavian Outflow Cannulation for Cardiopulmonary Bypass and Cardiac Support: A Computational Fluid Dynamics Study. Artif. Organs 2009.